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Articles (48)
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Large-scale purification and preliminary X-ray diffraction studies of human aspartylglucosaminidase

Tikkanen, Ritva, Rouvinen, Juha, Törrönen, Anneli, Kalkkinen, Nisse, Peltonen, Leena

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

1996

Langue:

english

Fichier:

PDF, 660 KB

english, 1996

Ein Protein erscheint in einem neuen Licht

Volker Herzog, Gregor Kirfel, Anton Schmitz, Ritva Tikkanen

Journal:

forschung

Année:

2004

Langue:

german

Fichier:

PDF, 219 KB

german, 2004

A Protein Appears in a Different Light

Volker Herzog, Gregor Kirfel, Anton Schmitz, Ritva Tikkanen

Journal:

German Research

Année:

2005

Langue:

english

Fichier:

PDF, 149 KB

english, 2005

The Dileucine Motif Within the Tail of MPR46 is Required for Sorting of the Receptor in Endosomes

Ritva Tikkanen, Stefanie Obermüller, Kristin Denzer, Rodolfo Pungitore, Hans J. Geuze, Kurt Von Figura, Stefan Höning

Journal:

Traffic

Année:

2000

Langue:

english

Fichier:

PDF, 490 KB

english, 2000

Cbl-associated protein is tyrosine phosphorylated by c-Abl and c-Src kinases

Inga Fernow, Ana Tomasovic, Ann Siehoff-Icking, Ritva Tikkanen

Journal:

BMC Cell Biology

Année:

2009

Langue:

english

Fichier:

PDF, 2.53 MB

english, 2009

Cytosolic and nuclear aggregation of the amyloid β-peptide following its expression in the endoplasmic reticulum

Andrea Bückig, Ritva Tikkanen, Volker Herzog, Anton Schmitz

Journal:

Histochemistry and Cell Biology

Année:

2002

Langue:

english

Fichier:

PDF, 483 KB

english, 2002

Polarized Transport of Alzheimer Amyloid Precursor Protein Is Mediated by Adaptor Protein Complex AP1-1B

Ann Icking, Monia Amaddii, Mika Ruonala, Stefan Höning, Ritva Tikkanen

Journal:

Traffic

Année:

2007

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2007

AP-1 and AP-3 Mediate Sorting of Melanosomal and Lysosomal Membrane Proteins into Distinct Post-Golgi Trafficking Pathways

Björn Chapuy, Ritva Tikkanen, Chris Mühlhausen, Dirk Wenzel, Kurt Von Figura, Stefan Höning

Journal:

Traffic

Année:

2008

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2008

Regulation of ubiquitin-binding proteins by monoubiquitination

Hoeller, Daniela, Crosetto, Nicola, Blagoev, Blagoy, Raiborg, Camilla, Tikkanen, Ritva, Wagner, Sebastian, Kowanetz, Katarzyna, Breitling, Rainer, Mann, Matthias, Stenmark, Harald

Journal:

Nature Cell Biology

Année:

2006

Langue:

english

Fichier:

PDF, 2.79 MB

english, 2006

AP-4 binds basolateral signals and participates in basolateral sorting in epithelial MDCK cells

Simmen, Thomas, Höning, Stefan, Icking, Ann, Tikkanen, Ritva, Hunziker, Walter

Journal:

Nature Cell Biology

Année:

2002

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2002

Three-dimensional structure of human lysosomal aspartylglucosaminidase

Oinonen, Carita, Tikkanen, Ritva, Rouvinen, Juha, Peltonen, Leena

Journal:

Natural Structural Biology

Année:

1995

Fichier:

PDF, 892 KB

1995

Hetero-oligomerization of reggie-1/flotillin-2 and reggie-2/flotillin-1 is required for their endocytosis

Tanja Babuke, Mika Ruonala, Melanie Meister, Monia Amaddii, Christina Genzler, Alessandro Esposito, Ritva Tikkanen

Journal:

Cellular Signalling

Année:

2009

Langue:

english

Fichier:

PDF, 893 KB

english, 2009

Dissecting the molecular function of reggie/flotillin proteins

Tanja Babuke, Ritva Tikkanen

Journal:

European Journal of Cell Biology

Année:

2007

Langue:

english

Fichier:

PDF, 480 KB

english, 2007

Reggie-1 and reggie-2 localize in non-caveolar rafts in epithelial cells: Cellular localization is not dependent on the expression of caveolin proteins

Inga Fernow, Ann Icking, Ritva Tikkanen

Journal:

European Journal of Cell Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2007

Oncogenic breakdowns in endocytic adaptor proteins

Nicola Crosetto, Ritva Tikkanen, Ivan Dikic

Journal:

FEBS Letters

Année:

2005

Langue:

english

Fichier:

PDF, 117 KB

english, 2005

Identification of Structural Elements in Nox1 and Nox4 Controlling Localization and Activity

Helmcke, Ina, Heumüller, Sabine, Tikkanen, Ritva, Schröder, Katrin, Brandes, Ralf P.

Journal:

Antioxidants & Redox Signaling

Année:

2009

Langue:

english

Fichier:

PDF, 463 KB

english, 2009

Phosphatidylinositol 3-Kinase dependent upregulation of the epidermal growth factor receptor upon Flotillin-1 depletion in breast cancer cells

Kurrle, Nina, Ockenga, Wymke, Meister, Melanie, Völlner, Frauke, Kühne, Sina, John, Bincy A, Banning, Antje, Tikkanen, Ritva

Journal:

BMC Cancer

Année:

2013

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2013

Flotillins bind to the dileucine sorting motif of β-site amyloid precursor protein-cleaving enzyme 1 and influence its endosomal sorting

John, Bincy A., Meister, Melanie, Banning, Antje, Tikkanen, Ritva

Journal:

FEBS Journal

Année:

2014

Langue:

english

Fichier:

PDF, 598 KB

english, 2014

Role of dynamin and clathrin in the cellular trafficking of flotillins

Meister, Melanie, Zuk, Alexandra, Tikkanen, Ritva

Journal:

FEBS Journal

Année:

2014

Langue:

english

Fichier:

PDF, 1.37 MB

english, 2014

Increased activity of mitogen activated protein kinase pathway in flotillin-2 knockout mouse model

Banning, Antje, Regenbrecht, Christian R.A., Tikkanen, Ritva

Journal:

Cellular Signalling

Année:

2014

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2014

Membrane and raft association of reggie-1/flotillin-2: role of myristoylation, palmitoylation and oligomerization and induction of filopodia by overexpression

NEUMANN-GIESEN, Carolin, FALKENBACH, Bianca, BEICHT, Peter, CLAASEN, Stephanie, LÜERS, Georg, STUERMER, Claudia A. O., HERZOG, Volker, TIKKANEN, Ritva

Journal:

Biochemical Journal

Année:

2004

Langue:

english

Fichier:

PDF, 283 KB

english, 2004

Intracellular Sorting of Aspartylglucosaminidase: The Role of N -Linked Oligosaccharides and Evidence of Man-6-P-Independent Lysosomal Targeting

TIKKANEN, RITVA, ENOMAA, NINA, RIIKONEN, AIJA, IKONEN, ELINA, PELTONEN, LEENA

Journal:

DNA and Cell Biology

Année:

1995

Langue:

english

Fichier:

PDF, 5.33 MB

english, 1995

Flotillin-1 facilitates toll-like receptor 3 signaling in human endothelial cells

Fork, Christian, Hitzel, Juliane, Nichols, Benjamin J., Tikkanen, Ritva, Brandes, Ralf P.

Journal:

Basic Research in Cardiology

Année:

2014

Langue:

english

Fichier:

PDF, 3.64 MB

english, 2014

Flotillins in Receptor Tyrosine Kinase Signaling and Cancer

Banning, Antje, Kurrle, Nina, Meister, Melanie, Tikkanen, Ritva

Journal:

Cells

Année:

2014

Langue:

english

Fichier:

PDF, 566 KB

english, 2014

Cholinergic Transactivation of the EGFR in HaCaT Keratinocytes Stimulates a Flotillin-1 Dependent MAPK-Mediated Transcriptional Response

Kühne, Sina, Ockenga, Wymke, Banning, Antje, Tikkanen, Ritva

Journal:

International Journal of Molecular Sciences

Année:

2015

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2015

Endocytic Trafficking of Membrane-Bound Cargo: A Flotillin Point of View

Meister, Melanie, Tikkanen, Ritva

Journal:

Membranes

Année:

2014

Langue:

english

Fichier:

PDF, 637 KB

english, 2014

Epidermal Growth Factor Receptor Transactivation Is Required for Mitogen-Activated Protein Kinase Activation by Muscarinic Acetylcholine Receptors in HaCaT Keratinocytes

Ockenga, Wymke, Kühne, Sina, Bocksberger, Simone, Banning, Antje, Tikkanen, Ritva

Journal:

International Journal of Molecular Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 4.46 MB

english, 2014

Mitogen-Activated Protein (MAP) Kinase Scaffolding Proteins: A Recount

Meister, Melanie, Tomasovic, Ana, Banning, Antje, Tikkanen, Ritva

Journal:

International Journal of Molecular Sciences

Année:

2013

Langue:

english

Fichier:

PDF, 886 KB

english, 2013

Functional Aspects of Membrane Association of Reggie/Flotillin Proteins

Banning, Antje, Tomasovic, Ana, Tikkanen, Ritva

Journal:

Current Protein & Peptide Science

Année:

2011

Langue:

english

Fichier:

PDF, 214 KB

english, 2011

Occupationally Oriented Medical Rehabilitation and Hairdressers’ Work Techniques–A one-and-a-half-year follow-up

Arokoski, Jari P. A., Nevala-Puranen, Nina, Danner, Rolf, Halonen, Merja, Tikkanen, Ritva

Journal:

International Journal of Occupational Safety and Ergonomics

Année:

1998

Fichier:

PDF, 3.21 MB

1998

Occupationally Oriented Medical Rehabilitation and Hairdressers’ Work Techniques–A one-and-a-half-year follow-up

Arokoski, Jari P. A., Nevala-Puranen, Nina, Danner, Rolf, Halonen, Merja, Tikkanen, Ritva

Journal:

International Journal of Occupational Safety and Ergonomics

Année:

1998

Langue:

english

Fichier:

PDF, 3.21 MB

english, 1998

A polycystin multiprotein complex constitutes a cholesterol-containing signalling microdomain in human kidney epithelia

Roitbak, Tamara, Surviladze, Zurab, Tikkanen, Ritva, Wandinger-Ness, Angela

Journal:

Biochemical Journal

Année:

2005

Langue:

english

Fichier:

PDF, 1.85 MB

english, 2005

Identification of Small Molecule Compounds for Pharmacological Chaperone Therapy of Aspartylglucosaminuria

Banning, Antje, Gülec, Christina, Rouvinen, Juha, Gray, Steven J., Tikkanen, Ritva

Journal:

Scientific Reports

Année:

2016

Langue:

english

Fichier:

PDF, 1.89 MB

english, 2016

Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes

Völlner, Frauke, Ali, Jawahir, Kurrle, Nina, Exner, Yvonne, Eming, Rüdiger, Hertl, Michael, Banning, Antje, Tikkanen, Ritva

Journal:

Scientific Reports

Année:

2016

Langue:

english

Fichier:

PDF, 2.15 MB

english, 2016

Amlexanox provides a potential therapy for nonsense mutations in the lysosomal storage disorder Aspartylglucosaminuria

Banning, Antje, Schiff, Manuel, Tikkanen, Ritva

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Année:

2017

Langue:

english

Fichier:

PDF, 5.19 MB

english, 2017

Transcriptional Regulation of Flotillins by the Extracellularly Regulated Kinases and Retinoid X Receptor Complexes

Banning, Antje, Ockenga, Wymke, Finger, Fabian, Siebrasse, Philipp, Tikkanen, Ritva, Buday, Laszlo

Journal:

PLoS ONE

Année:

2012

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2012

Flotillins Directly Interact with γ-Catenin and Regulate Epithelial Cell-Cell Adhesion

Kurrle, Nina, Völlner, Frauke, Eming, Rüdiger, Hertl, Michael, Banning, Antje, Tikkanen, Ritva, Hotchin, Neil A.

Journal:

PLoS ONE

Année:

2013

Langue:

english

Fichier:

PDF, 14.41 MB

english, 2013

Random Splicing of Several Exons Caused by a Single Base Change in the Target Exon of CRISPR/Cas9 Mediated Gene Knockout

Kapahnke, Marcel, Banning, Antje, Tikkanen, Ritva

Journal:

Cells

Année:

2016

Langue:

english

Fichier:

PDF, 3.52 MB

english, 2016

Functional Analysis of the Ser149/Thr149 Variants of Human Aspartylglucosaminidase and Optimization of the Coding Sequence for Protein Production

Banning, Antje, König, Jan F., Gray, Steven J., Tikkanen, Ritva

Journal:

International Journal of Molecular Sciences

Année:

2017

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2017

Altered Expression of Ganglioside Metabolizing Enzymes Results in GM3 Ganglioside Accumulation in Cerebellar Cells of a Mouse Model of Juvenile Neuronal Ceroid Lipofuscinosis

Somogyi, Aleksandra, Petcherski, Anton, Beckert, Benedikt, Huebecker, Mylene, Priestman, David, Banning, Antje, Cotman, Susan, Platt, Frances, Ruonala, Mika, Tikkanen, Ritva

Journal:

International Journal of Molecular Sciences

Année:

2018

Langue:

english

Fichier:

PDF, 5.95 MB

english, 2018

Revisiting the Endocytosis of the M2 Muscarinic Acetylcholine Receptor

Ockenga, Wymke, Tikkanen, Ritva

Journal:

Membranes

Année:

2015

Langue:

english

Fichier:

PDF, 7.86 MB

english, 2015

Flotillins Regulate Focal Adhesions by Interacting with α-Actinin and by Influencing the Activation of Focal Adhesion Kinase

Banning, Antje, Babuke, Tanja, Kurrle, Nina, Meister, Melanie, Ruonala, Mika, Tikkanen, Ritva

Journal:

Cells

Année:

2018

Langue:

english

Fichier:

PDF, 40.97 MB

english, 2018

Non-Neuronal Functions of the M2 Muscarinic Acetylcholine Receptor

Ockenga, Wymke, Kühne, Sina, Bocksberger, Simone, Banning, Antje, Tikkanen, Ritva

Journal:

Genes

Année:

2013

Langue:

english

Fichier:

PDF, 748 KB

english, 2013

Immortalized Human hTert/KER-CT Keratinocytes a Model System for Research on Desmosomal Adhesion and Pathogenesis of Pemphigus Vulgaris

Beckert, Benedikt, Panico, Francesca, Pollmann, Robert, Eming, Rüdiger, Banning, Antje, Tikkanen, Ritva

Journal:

International Journal of Molecular Sciences

Année:

2019

Langue:

english

Fichier:

PDF, 5.55 MB

english, 2019

Mitogen-Activated Protein Kinases: Functions in Signal Transduction and Human Diseases

Tikkanen, Ritva, Nikolic-Paterson, David J.

Journal:

International Journal of Molecular Sciences

Année:

2019

Langue:

english

Fichier:

PDF, 170 KB

english, 2019

Succinic Semialdehyde Dehydrogenase Deficiency: An Update

DidiÃ¡Å¡ovÃ¡, Miroslava, Banning, Antje, Brennenstuhl, Heiko, Jung-Klawitter, Sabine, Cinquemani, Claudio, Opladen, Thomas, Tikkanen, Ritva

Journal:

Cells

Année:

2020

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2020

Statistical Permutation Test Reveals Progressive and Region-Specific Iron Accumulation in the Thalami of Children with Aspartylglucosaminuria

Sairanen, Viljami, Tokola, Anna, Tikkanen, Ritva, Laine, Minna, Autti, Taina

Journal:

Brain Sciences

Année:

2020

Fichier:

PDF, 1.60 MB

2020

Succinic Semialdehyde Dehydrogenase Deficiency: In Vitro and In Silico Characterization of a Novel Pathogenic Missense Variant and Analysis of the Mutational Spectrum of ALDH5A1

Brennenstuhl, Heiko, Didiasova, Miroslava, Assmann, Birgit, Bertoldi, Mariarita, Molla, Gianluca, Jung-Klawitter, Sabine, Kuseyri HÃ¼bschmann, Oya, SchrÃ¶ter, Julian, Opladen, Thomas, Tikkanen, Ritva

Journal:

International Journal of Molecular Sciences

Année:

2020

Fichier:

PDF, 2.41 MB

2020